Content material:
Chapter I Acridines (pages 9–108): N. R. Raulins
Chapter II Aminoacridines (pages 109–140): B. Adcock
Chapter III 9?Acridanones (pages 141–377): J. M. F. Gagan
Chapter IV The Acridine Alkaloids (pages 379–432): J. E. Saxton
Chapter V Acridinium Salts and decreased Acridines (pages 433–517): I. A. Selby
Chapter VI Biacridines (pages 519–528): Frank Mccapra
Chapter VII Benzacridines and Condensed Acridines (pages 529–577): D. A. Robinson
Chapter VIII Acridine Dyes (pages 579–613): B. D. Tilak and N. R. Ayyangar
Chapter IX Chemiluminescent Reactions of Acridines (pages 615–630): Frank Mccapra
Chapter X Ultraviolet and visual Absorption Spectra (pages 631–664): Margaret L. Bailey
Chapter XI The Infrared Spectra of Acridines (pages 665–685): R. M. Acheson
Chapter XII The Nuclear Magnetic Resonance Spectra of Acridines (pages 687–707): R. M. Acheson
Chapter XIII The Mass Spectra of Acridines (pages 709–721): R. G. Bolton
Chapter XIV The interplay of Acridines with Nucleic Acids (pages 723–757): A. R. Peacocke
Chapter XV Acridines and Enzymes (pages 759–787): B. H. Nicholson
Chapter XVI The Antibacterial motion of Acridines (pages 789–813): A. C. R. Dean
Chapter XVII Carcinogenic and Anticarcinogenic houses of Acridines (pages 815–828): David B. Clayson
Chapter XVIII Acridine Antimalarials (pages 829–850): David W. Henry

Show description

Read Online or Download Chemistry of Heterocyclic Compounds: Acridines, Volume 9, Second Edition PDF

Similar chemistry books

LSD-25 & Tryptamine Syntheses Overview & Reference

LSD-25 & Tryptamine Syntheses evaluate & Reference is the main complete reference advisor at the syntheses of LSD-25. Reactions are defined together with a assessment of the duty strength file: Narcotics and Drug Abuse, Annotations and Consultants' Papers. a number of the reactions comprise: Synthesis of N,N-dialkyl substututed lysergamides.

Electronic and Magnetic Properties of Chiral Molecules and Supramolecular Architectures

Time-Dependent Density useful reaction conception for digital Chiroptical homes of Chiral Molecules, by way of Jochen Autschbach, Lucia Nitsch–Velasquez, and Mark Rudolph; contemporary Theoretical and Experimental Advances within the digital round Dichroisms of Planar Chiral Cyclophanes, by way of Yoshihisa Inoue and Tadashi Mori; G-C content material self sufficient Long-Range cost move via DNA, via Kiyohiko Kawai and Tetsuro Majima; move of Chirality for reminiscence and Separation, by way of Rosaria Lauceri, Alessandro D’Urso, Angela Mammana and Roberto Purrello; Vibrational round Dichroism Spectroscopy four of Chiral Molecules, through Guochun Yang and Yunjie Xu; Spin Selective Electron Transmission via Monolayers of Chiral Molecules, through Ron Naaman and Zeev Vager; Chiral keep an eye on of present move in Molecules, via Vered Ben-Moshe, David N.

Computational Studies in Organometallic Chemistry

The sequence constitution and Bonding publishes severe reports on themes of analysis all in favour of chemical constitution and bonding. The scope of the sequence spans the whole Periodic desk and addresses constitution and bonding matters linked to all the components. It additionally focuses recognition on new and constructing parts of recent structural and theoretical chemistry resembling nanostructures, molecular electronics, designed molecular solids, surfaces, steel clusters and supramolecular buildings.

Additional info for Chemistry of Heterocyclic Compounds: Acridines, Volume 9, Second Edition

Sample text

237Rieche and M ~ e l l e have r ~ ~prepared ~ methylacridines by passing the vapors of aromatic amines, diluted with nitrogen, over aluminum oxide at 440": o-toluidine -+ 10% yield of 4 3 dimethylacridine; p-toluidine --+ 10% of 2,7-dimethylacridine; p-xylidine --+ 1,4,5,8-tetramethylacridine(63). 53 2 . ~*l Phloroglucinol and 2-aminobenzaldehyde, in an almost complementary reaction, were found to give 1,3-dihydroxyacridine in the presence of sodium hyd r o ~ i d e . * This ~ * reaction was fully investigated later,243the reactants being allowed to stand in aqueous solution at room temperature for 5 days at definite pH values, 4-13.

Methods of Preparation of Acridines 51 More recent applications of selenium dehydrogenation of perhydroacridines222 and tetrahydroa~ridine22~ have been reported, but there is no indication that yields of acridines are improved. 221Yields of 5 to 17% of acridine have been obtained when tetra- and octa-hydroacridines were heated in boiling xylene with 5-10y0 excess of c h l 0 r a n i 1 . j ~~ used chloranil in the dehydrogenation of diethyl acridan-9-phosphonate. Decarboxylation and distillation with lead dioxidezz6has transformed appropriately substituted 1,2,3,4-tetrahydroacridine-9-carboxylic acids into 2- and 3-methylacridine ; this reagent also aromatized some reduced benza c r i d i n e ~Chloranil .

Frothing, due largely to the evolution of carbon dioxide, is eliminated, and the formation of oxanilides is precluded. 3 moles) and formic acid (1-2 moles), in sufficient glycerol to ensure homogeneity, to 155-175” for about an hour. 164A list of acridines prepared by this method is given in Table 111. 163 The mechanism of the reaction has been investigated in some The first stage is undoubtedly the production of 3-aminoformanilide (21). This compound was isolated when the reaction was not allowed to go to completion ; when treated with rn-phenylenediamine under the usual reaction conditions, it gave a larger yield of 3,6-diaminoacridine than could be obtained from formic acid and the diamine.

Download PDF sample

Rated 4.09 of 5 – based on 31 votes